Thursday, January 24, 2019

24genetics Review

My European countries map from 24genetics
24genetics offer DNA tests for health and ancestry related reports, and also accept raw DNA uploads from other companies for more limited report options. For the uploads, they only offer reports on ancestry, sport, skin, nutrition, and talent/personality. If you buy a test with them, you can also get health and drug response reports, but be aware that each one costs $149 - $199, and if you want all the reports, the "all in one" pack costs a whopping $399. This seems very expensive, and if you're looking for a health report, I wouldn't buy tests through this company, there are less expensive venues. 23andMe costs half this for their ancestry and health, and is on sale often enough you can get it for even less. 23andMe may not include all same reports, but you can then upload your data to other, inexpensive sources like Promethease for more.

Most of the reports from uploaded DNA say they accept data from 23andMe or AncestryDNA, except the ancestry report, which says it will accept DNA from 23andMe, FamilyTreeDNA, AncestryDNA, or MyHeritage. The ancestry test costs $49, and the rest cost $69. You can order a promo pack including ancestry, sport, nutrition, and skin for $99. These also seem expensive for what you get, considering they don't have to run your DNA through a lab, so I only purchased the ancestry report and uploaded my raw DNA data from 23andMe.

The report is sent in an email as a PDF, much like how DNATribes before they discontinued their upload offer. In the PDF, you get an ethnic break down of your DNA first on a continental level called "Global Vision", then a country level, and finally a regional level. Like most ethnicity reports, they say the results date back "hundreds and even thousands of years".

My country results from 24genetics
My continental results (deserving of all caps, apparently) say:

EUROPE 99.20%
ASIA 0.80%

Most likely, the Asian results are just noise. You'll see in the country and regional break down that my Asian results are in a part of Georgia, in the Caucasus area (just above the Middle East), so it's possible this is related to my southern Italian ancestry, but given the small percentage, it may just be noise and not mean anything.

My country results:

Great Britain 33.80%
Italy 30.00%
Austria 17.10%
Greece 8.20%
Netherlands 5.60%
Switzerland 2.30%
Finland 2.20%
Georgia 0.80%

The top two results are very accurate, my family tree is indeed roughly 32% British, and I did in fact inherit about 32% of my DNA from my Italian grandmother. But rest of the results aren't very consistent with my known ancestry. The smaller results could just be noise, and I'm guessing the Austria result is coming from my Germanic ancestry. I'm not sure where the Greek is coming from, since the only Mediterranean ancestry I have is already fully accounted for in my Italy results.

AncestryDNA's PCA chart showing reference panel
populations and their genetic distance to each other
The main thing it's missing is my Norwegian ancestry. Though I had one Norwegian great grandfather, my Scandinavian results often come back lower than the "expected" 12.5% on most ethnicity reports, so perhaps I inherited less from him than expected. I do get a trace amount in Finland, but as you'll see below, it's in an eastern part of Finland, which seems like it would have more in common genetically with Russia than Norway. In fact, AncestryDNA used to group Finland and NW Russia together. Although they now have separated the two groups, their PCA chart (left) shows that the Finnish group has no overlap with Scandinavia (let alone Norway), but does have some minor overlap with the Baltic States (northeast Europe, such as Estonia, Latvia, Lithuania). So I doubt there's any connection to my Norwegian ancestor. Norway usually has more in common genetically with Germanic Europe and Britain, so maybe the Netherlands results are coming from my Norwegian ancestry, but I do also have Dutch ancestry, though much further back on my tree.

Maps are provided for the results, first showing the highlighted countries on a global scale (above right), and then zooming in on Europe (above left). I guess my one small result in West Asia didn't warrant a zoom in.

My regional results
My regional results:

Essex Medieval 32.30%
Tyrol 17.10%
Apulia 15.80%
Lombardy 13.60%
Utrecht 5.40%
Crete 3.20%
Kythera 3.00%
Romandy 2.30%
Finland Karelia 2.20%
Andros 2.00%
Cornwall 1.50%
Georgia Svaneti 0.80%
Treviso 0.60%
Groningen 0.20%

Essex Medieval is an interesting result because it specifies a time period as well as location. I wonder why the other results don't include a time period? I do indeed have ancestry from Essex, although there's a few branches from there, they are all from fairly far back on my tree, in the 1500s. I suppose that's consistent with the Medieval timeline, however, they seem to be attributing almost all my British ancestry to Medieval Essex, yet I have British ancestry from many other locations, some from much more recent time periods too (which should account for more of my DNA).

My European regional map
Tyrol is a region of western Austria which borders Germany and Switzerland, both places where I do have ancestry from, so I'm assuming that's where this result is coming from.

Apulia is an area of southeast Italy. I have no known ancestry from there, but my Italian ancestry is indeed southern/Sicilian, not northern, so I'll give it points for that. However, Lombardy and Treviso are a part of northern Italy, where I have no known ancestry.

Next is Utrecht, a city in the Netherlands. I don't know where in the Netherlands most of my Dutch branches come from, but one of them is actually from Utrecht, and another from Amsterdam. But let's face it, the Netherlands is a pretty small country (though it was once larger), so I'm not really sure how distinct DNA from different parts of it really are from one another - Amsterdam is really not that far from Utrecht (about 27 miles). Although this is a small percentage, my Dutch ancestry is from far back on my tree, so I would expect it to be a small percentage, if it would show up at all. I also get a very small hit (possibly noise) for Groningen in the Netherlands, where I don't have any known ancestry.

My Asian regional map, probably
noise
Now we get into percentages so low they may only be noise. Crete, Kythera, and Andros are all in Greece, which again, I have no known connection to. Maybe some of it is related to my Italian ancestry, but it can't be all of it, or that tips my Italian percentage over the edge of being too much. Romandy is a French speaking part of Switzerland, and I do have both French and Swiss ancestry (again, far back on my tree), so perhaps there's some legitimacy to this. Karelia is an eastern part of Finland I have zero connection to (again, it's unlikely it's from my Norwegian ancestry, and I have no known ancestry in Eastern Europe). Cornwall is the southwestern most part of England, which I have no known ancestry from, but could still be a legitimate part of my British DNA. Svaneti is a historical area of Georgia, which may just be noise or could be coming from my Italian ancestry.

Overall, I feel like my top most results from this company are accurate but it's missing significant locations and the smallest percentages are likely just noise. An interesting assessment, especially the more specific break down that you don't always get from other companies, but as with any ethnicity report, don't take it too literally. Worth the money? Probably not, maybe if it was cheaper.

2 comments:

  1. You say 24 genetics only accepts 23andme raw data but I bet it will accept ancestryDNA raw data converted to 23andme format. AFAIK, the dna.land website will convert ancestryDNA format to 23andme format for free and there should be other tools online to do it too.

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  2. I uploaded my raw data from MyHeritage to get a more accurate geographical breakdown. A total waste of money. I have researched all branches of my family, including wives' families, back five to eight generations and they are 95% from south east England. 24genetics.com gives me mainly Lancashire in the north of England. When I queried this, they wrote back (22nd May) saying 'I'm sending your query to the Ancestry team for further clarification'. Nothing more from them since.

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